STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pot-3POT1PC domain-containing protein. (215 aa)    
Predicted Functional Partners:
pot-1
Protection of telomeres homolog 1; Telomeric DNA-binding protein, which binds to single-stranded C-rich repeat sequences, with high specificity to the 5'-GCCTAA-3' sequence. Repeat sequence binding can be at the 5' or 3' telomeric end. May have a role in protecting the 5' end of the C-rich strand of the telomere. Acts redundantly with pot-2 to negatively regulate telomerase-mediated telomere extension. Also regulates telomere length by the telomerase-independent telomere maintenance pathway called ALT (alternative lengthening of telomeres). Through sun-1, anchors telomeres to the nucle [...]
   
  
 0.893
F10E9.4
Uncharacterized protein F10E9.4.
      
 0.850
F12F6.7
Probable DNA polymerase delta small subunit; The function of the small subunit is not yet clear; Belongs to the DNA polymerase delta/II small subunit family.
   
  
 0.814
F25B5.5
CDK5RAP1-like protein; Potential regulator of CDK5 activity; Belongs to the methylthiotransferase family. MiaB subfamily.
  
  
 0.812
W08A12.2
Uncharacterized protein.
      
 0.805
ZK470.2
Uncharacterized protein.
      
 0.805
exos-1
ECR1_N domain-containing protein.
   
  
 0.765
cku-70
Ku domain-containing protein.
   
 
 0.729
rmh-2
DUF1767 domain-containing protein.
   
  
 0.715
exos-2
EXOSome (Multiexonuclease complex) component.
   
  
 0.708
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.