STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbm-26C3H1-type domain-containing protein. (721 aa)    
Predicted Functional Partners:
rbm-22
RNA Binding Motif protein homolog.
   
  
 0.788
pabp-2
RRM domain-containing protein.
   
 
 0.717
F10D2.10
Uncharacterized protein.
      
 0.697
mig-38
Abnormal cell migration protein 38; During gonad development, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody which allows for the formation of gonad arms. Role in gonad DTC migration may be in association with integrin related proteins ina-1 and mig-15.
   
  
 0.678
ins-14
INSulin related.
      
 0.616
mtr-4
mRNA transport homolog 4.
   
 
 0.615
Y111B2A.10
Uncharacterized protein.
      
 0.549
ceh-44
Homeobox protein cut-like ceh-44; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family.
   
  
 0.539
tsp-14
Tetraspanin-14; Together with tsp-12, regulates cell fate specification in the postembryonic mesodermal M lineage, body size and male development, probably by positively modulating BMP-like Sma/Mab signaling. Together with tsp-12, probably acts by modulating the activation of glp-1, Notch-like receptor, to regulate germline maturation ; Belongs to the tetraspanin (TM4SF) family.
      
 0.538
skih-2
SKI (Yeast SuperKIller) Helicase homolog.
   
 
 0.514
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.