node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
act-5 | dhc-3 | T25C8.2.2 | B0365.7.1 | ACTin. | Dynein Heavy Chain. | 0.800 |
act-5 | dli-1 | T25C8.2.2 | C39E9.14a.2 | ACTin. | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. | 0.511 |
act-5 | dnc-1 | T25C8.2.2 | ZK593.5b.1 | ACTin. | CAP-Gly domain-containing protein. | 0.575 |
act-5 | dnc-2 | T25C8.2.2 | C28H8.12.1 | ACTin. | Probable dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity); Belongs to the dynactin subunit 2 family. | 0.696 |
act-5 | klc-2 | T25C8.2.2 | C18C4.10b.1 | ACTin. | Kinesin light chain; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (Probable). The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Recruits unc-83 (within the unc-83-unc-84 LINC complex) to the nuclear envelope during nuclear migration to mediate the link between the nuclear envelope and the microtubule cytoskeleton in hypodermal precursor cells. | 0.830 |
act-5 | unc-116 | T25C8.2.2 | R05D3.7.1 | ACTin. | Kinesin heavy chain; Microtubule-dependent motor protein required for organelle transport. Plays a role in endosome transport. Required for the transport of mitochondria along the axon of motor neurons. Involved in the nuclear migration of hyp7 hypodermal precursor cells. Required for the formation of dendritic branches of PVD sensory neurons. In non-ciliated neurons such as the PVD and PHC neurons, required for the organization of minus-end out microtubules in dendrites. Involved in the localization of unc-33 to neurites. | 0.728 |
dhc-3 | act-5 | B0365.7.1 | T25C8.2.2 | Dynein Heavy Chain. | ACTin. | 0.800 |
dhc-3 | dlc-1 | B0365.7.1 | T26A5.9.3 | Dynein Heavy Chain. | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] | 0.889 |
dhc-3 | dli-1 | B0365.7.1 | C39E9.14a.2 | Dynein Heavy Chain. | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. | 0.938 |
dhc-3 | dnc-1 | B0365.7.1 | ZK593.5b.1 | Dynein Heavy Chain. | CAP-Gly domain-containing protein. | 0.918 |
dhc-3 | dnc-2 | B0365.7.1 | C28H8.12.1 | Dynein Heavy Chain. | Probable dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity); Belongs to the dynactin subunit 2 family. | 0.852 |
dhc-3 | dylt-1 | B0365.7.1 | F13G3.4.1 | Dynein Heavy Chain. | DYnein Light chain (Tctex type). | 0.867 |
dhc-3 | dyrb-1 | B0365.7.1 | T24H10.6.1 | Dynein Heavy Chain. | Dynein light chain roadblock; Belongs to the GAMAD family. | 0.906 |
dhc-3 | klc-2 | B0365.7.1 | C18C4.10b.1 | Dynein Heavy Chain. | Kinesin light chain; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (Probable). The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Recruits unc-83 (within the unc-83-unc-84 LINC complex) to the nuclear envelope during nuclear migration to mediate the link between the nuclear envelope and the microtubule cytoskeleton in hypodermal precursor cells. | 0.817 |
dhc-3 | unc-116 | B0365.7.1 | R05D3.7.1 | Dynein Heavy Chain. | Kinesin heavy chain; Microtubule-dependent motor protein required for organelle transport. Plays a role in endosome transport. Required for the transport of mitochondria along the axon of motor neurons. Involved in the nuclear migration of hyp7 hypodermal precursor cells. Required for the formation of dendritic branches of PVD sensory neurons. In non-ciliated neurons such as the PVD and PHC neurons, required for the organization of minus-end out microtubules in dendrites. Involved in the localization of unc-33 to neurites. | 0.850 |
dhc-3 | xbx-1 | B0365.7.1 | F02D8.3.1 | Dynein Heavy Chain. | X-BoX promoter element regulated. | 0.822 |
dlc-1 | dhc-3 | T26A5.9.3 | B0365.7.1 | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] | Dynein Heavy Chain. | 0.889 |
dlc-1 | dli-1 | T26A5.9.3 | C39E9.14a.2 | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. | 0.872 |
dlc-1 | dnc-1 | T26A5.9.3 | ZK593.5b.1 | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] | CAP-Gly domain-containing protein. | 0.830 |
dlc-1 | dnc-2 | T26A5.9.3 | C28H8.12.1 | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] | Probable dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity); Belongs to the dynactin subunit 2 family. | 0.591 |