node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ceh-32 | dac-1 | W05E10.3.1 | B0412.1a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Ski_Sno domain-containing protein. | 0.655 |
ceh-32 | eya-1 | W05E10.3.1 | C49A1.4a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.934 |
ceh-32 | unc-39 | W05E10.3.1 | F56A12.1.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox protein unc-39; Probable transcription factor required for differentiation and migration of neuronal cells, such as RID and CAN neurons. Specifically, plays a role in the terminal differentiation of RID peptidergic neurons. Also required for CAN neuron axon guidance. | 0.411 |
ceh-33 | dac-1 | C10G8.7.1 | B0412.1a.1 | Homeobox protein ceh-33. | Ski_Sno domain-containing protein. | 0.801 |
ceh-33 | eya-1 | C10G8.7.1 | C49A1.4a.1 | Homeobox protein ceh-33. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.919 |
ceh-34 | dac-1 | C10G8.6.1 | B0412.1a.1 | Homeobox protein ceh-34; Acts as a transcription regulator. Binds to the cis-regulatory element of proapoptotic factor egl-1 gene and together with eya-1 activates egl-1 expression to promote motor neuron M4 sister cell apoptosis. Also promotes apoptosis of I1 pharyngeal neuron sister cell. Together with eya- 1, required to specify the coelomocyte fate in embryonic and postembryonic precursors. Belongs to the SIX/Sine oculis homeobox family. | Ski_Sno domain-containing protein. | 0.799 |
ceh-34 | eya-1 | C10G8.6.1 | C49A1.4a.1 | Homeobox protein ceh-34; Acts as a transcription regulator. Binds to the cis-regulatory element of proapoptotic factor egl-1 gene and together with eya-1 activates egl-1 expression to promote motor neuron M4 sister cell apoptosis. Also promotes apoptosis of I1 pharyngeal neuron sister cell. Together with eya- 1, required to specify the coelomocyte fate in embryonic and postembryonic precursors. Belongs to the SIX/Sine oculis homeobox family. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.991 |
ceh-9 | dac-1 | Y65B4BR.9.1 | B0412.1a.1 | Homeobox protein ceh-9. | Ski_Sno domain-containing protein. | 0.621 |
ceh-9 | mbr-1 | Y65B4BR.9.1 | T01C1.2.1 | Homeobox protein ceh-9. | Mblk-1-related factor 1; May act as transcription activator (By similarity). Plays a role in neurogenesis by regulating neurite pruning between left and right AIM neurons and left and right RIF neurons during larval development. Regulates olfactory plasticity. | 0.632 |
cla-1 | dac-1 | F45E4.3a.1 | B0412.1a.1 | Protein clarinet; Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons. The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse. Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions. Regulat [...] | Ski_Sno domain-containing protein. | 0.660 |
cla-1 | oig-8 | F45E4.3a.1 | T19D12.7.2 | Protein clarinet; Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons. The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse. Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions. Regulat [...] | Ig-like domain-containing protein. | 0.550 |
dac-1 | ceh-32 | B0412.1a.1 | W05E10.3.1 | Ski_Sno domain-containing protein. | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.655 |
dac-1 | ceh-33 | B0412.1a.1 | C10G8.7.1 | Ski_Sno domain-containing protein. | Homeobox protein ceh-33. | 0.801 |
dac-1 | ceh-34 | B0412.1a.1 | C10G8.6.1 | Ski_Sno domain-containing protein. | Homeobox protein ceh-34; Acts as a transcription regulator. Binds to the cis-regulatory element of proapoptotic factor egl-1 gene and together with eya-1 activates egl-1 expression to promote motor neuron M4 sister cell apoptosis. Also promotes apoptosis of I1 pharyngeal neuron sister cell. Together with eya- 1, required to specify the coelomocyte fate in embryonic and postembryonic precursors. Belongs to the SIX/Sine oculis homeobox family. | 0.799 |
dac-1 | ceh-9 | B0412.1a.1 | Y65B4BR.9.1 | Ski_Sno domain-containing protein. | Homeobox protein ceh-9. | 0.621 |
dac-1 | cla-1 | B0412.1a.1 | F45E4.3a.1 | Ski_Sno domain-containing protein. | Protein clarinet; Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons. The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse. Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions. Regulat [...] | 0.660 |
dac-1 | dnj-11 | B0412.1a.1 | F38A5.13.1 | Ski_Sno domain-containing protein. | DNaJ domain (Prokaryotic heat shock protein). | 0.613 |
dac-1 | eya-1 | B0412.1a.1 | C49A1.4a.1 | Ski_Sno domain-containing protein. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.942 |
dac-1 | mbr-1 | B0412.1a.1 | T01C1.2.1 | Ski_Sno domain-containing protein. | Mblk-1-related factor 1; May act as transcription activator (By similarity). Plays a role in neurogenesis by regulating neurite pruning between left and right AIM neurons and left and right RIF neurons during larval development. Regulates olfactory plasticity. | 0.638 |
dac-1 | oig-8 | B0412.1a.1 | T19D12.7.2 | Ski_Sno domain-containing protein. | Ig-like domain-containing protein. | 0.672 |