STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0546.4Protein yippee-like B0546.4. (161 aa)    
Predicted Functional Partners:
mai-2
ATPase inhibitor mai-2, mitochondrial; Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria. Activity is pH dependent.
   
  
 0.813
pcm-1
Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. This enzyme does not act on D-aspartyl residues.
   
  
 0.740
Y54E5A.7
Uncharacterized protein.
   
 
 0.672
Y39H10A.6
WD_REPEATS_REGION domain-containing protein.
   
 
 0.662
T07D1.2
Zf-RING_UBOX domain-containing protein.
    
 
 0.592
tag-304
Uncharacterized protein.
   
 
 0.489
sqst-2
ZZ-type domain-containing protein.
   
   0.460
memo-1
Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family.
   
  
 0.443
maea-1
MAEA (MAcrophage Erythroblast Attacher protein) homolog.
   
 
 0.415
M01H9.3
Uncharacterized protein.
   
    0.408
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.