STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acs-7Fatty Acid CoA Synthetase family. (540 aa)    
Predicted Functional Partners:
pks-1
PolyKetide Synthase.
  
 0.943
npp-11
Nuclear Pore complex Protein.
   
 
 0.906
acox-1.1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.893
Y48A6B.9
Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  
 
 0.865
C23H4.2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.859
acox-3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.841
daf-22
Non-specific lipid-transfer protein-like 2; Catalyzes the thiolytic cleavage of 3-ketoacyl-CoA with 8-16 carbon residues in the acyl group using a ping-pong mechanism whereby binding to 3-ketooctanoyl-CoA results in the release of acetyl-CoA and the subsequent addition of CoA produces 3-ketohexanohyl-CoA. Involved in the biosynthesis of the dauer pheromone by providing short chains of fatty acid that are attached to the ascarylose sugars of the pheromone. Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.822
E01G6.3
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.816
acox-1.3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.803
ech-8
Enoyl-CoA Hydratase.
  
 0.793
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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