STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C02B8.6Uncharacterized RING finger protein C02B8.6. (347 aa)    
Predicted Functional Partners:
B0334.4
PRELI/MSF1 domain-containing protein.
      
 0.852
srv-1
Serpentine receptor class V-1.
      
 0.852
Y48A6B.8
Uncharacterized protein.
      
 0.852
sri-19
Serpentine Receptor, class I.
      
 0.852
kdin-1
ANK_REP_REGION domain-containing protein.
    
 
 0.836
best-3
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
      
 0.806
gsp-1
Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Dephosphorylates translation initiation factor eIF2alpha. Involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Belongs to the PPP phosphatase family. PP-1 subfamily.
   
  
 0.669
ugt-8
UDP-GlucuronosylTransferase.
      
 0.669
nhr-31
Nuclear hormone receptor family member nhr-31; Orphan nuclear receptor.
      
 0.667
F16F9.1
LITAF domain-containing protein.
   
  
 0.663
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.