STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sup-18Iodotyrosine dehalogenase 1 homolog; May contribute to coordination of muscle contraction as regulatory subunit of the nonessential sup-9 potassium channel complex. May act downstream of sup-10. (325 aa)    
Predicted Functional Partners:
sup-10
Putative potassium channel regulatory protein sup-10; May contribute to coordination of muscle contraction as regulatory subunit of a nonessential potassium channel complex.
  
  
 0.973
sup-9
Two pore potassium channel protein sup-9; Potassium channel involved in coordination of muscle contraction. Activity is regulated by sup-18 ; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
  
 0.965
R10H10.6
Flavokinase domain-containing protein.
    
 0.915
unc-93
Putative potassium channel regulatory protein unc-93; May contribute to coordination of muscle contraction as regulatory subunit of a nonessential potassium channel complex. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord ; Belongs to the unc-93 family.
   
  
 0.910
Y73F8A.27
2Fe-2S ferredoxin-type domain-containing protein.
    
 0.893
mmab-1
Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.857
F52H2.4
Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
     
 0.846
ZK822.5
Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.846
isp-1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.838
C24A3.4
Uncharacterized protein.
   
 
 0.819
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.