STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C03H5.3Uncharacterized protein. (287 aa)    
Predicted Functional Partners:
F53H1.3
UDENN domain-containing protein.
   
  
 0.702
ari-2
Potential E3 ubiquitin-protein ligase ariadne-2; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBC-2/UBE2L3, and then transfers it to substrates. Belongs to the RBR family. Ariadne subfamily.
   
  
 0.663
rbpl-1
Retinoblastoma Binding Protein Like.
      
 0.589
ent-5
Equilibrative Nucleoside Transporter.
      
 0.586
aka-1
FYVE-type domain-containing protein.
   
  
 0.583
lbp-6
Fatty acid-binding protein homolog 6.
      
 0.467
F10E7.5
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
   
    0.446
C16C10.2
Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.
   
    0.418
C56A3.5
Uncharacterized protein.
   
    0.412
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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