node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0228.7 | C04E6.7 | B0228.7.3 | C04E6.7.1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein. | 0.550 |
B0228.7 | F32D1.5 | B0228.7.3 | F32D1.5a.1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.751 |
B0228.7 | K02D7.1 | B0228.7.3 | K02D7.1b.1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.619 |
B0228.7 | T22D1.3 | B0228.7.3 | T22D1.3a.1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.754 |
B0228.7 | ampd-1 | B0228.7.3 | C34F11.3d.1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.674 |
C04E6.7 | B0228.7 | C04E6.7.1 | B0228.7.3 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.550 |
C04E6.7 | C17E4.10 | C04E6.7.1 | C17E4.10a.2 | Uncharacterized protein. | Uncharacterized protein. | 0.529 |
C04E6.7 | F26H9.5 | C04E6.7.1 | F26H9.5.1 | Uncharacterized protein. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.753 |
C04E6.7 | F32D1.5 | C04E6.7.1 | F32D1.5a.1 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.551 |
C04E6.7 | K02D7.1 | C04E6.7.1 | K02D7.1b.1 | Uncharacterized protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.563 |
C04E6.7 | T22D1.3 | C04E6.7.1 | T22D1.3a.1 | Uncharacterized protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.551 |
C04E6.7 | ampd-1 | C04E6.7.1 | C34F11.3d.1 | Uncharacterized protein. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.516 |
C04E6.7 | cor-1 | C04E6.7.1 | R01H10.3c.2 | Uncharacterized protein. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.539 |
C04E6.7 | mel-32 | C04E6.7.1 | C05D11.11b.2 | Uncharacterized protein. | Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family. | 0.720 |
C04E6.7 | ndx-9 | C04E6.7.1 | F13H10.2a.1 | Uncharacterized protein. | NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.713 |
C17E4.10 | C04E6.7 | C17E4.10a.2 | C04E6.7.1 | Uncharacterized protein. | Uncharacterized protein. | 0.529 |
C17E4.10 | F26H9.5 | C17E4.10a.2 | F26H9.5.1 | Uncharacterized protein. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.431 |
F26H9.5 | C04E6.7 | F26H9.5.1 | C04E6.7.1 | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Uncharacterized protein. | 0.753 |
F26H9.5 | C17E4.10 | F26H9.5.1 | C17E4.10a.2 | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Uncharacterized protein. | 0.431 |
F26H9.5 | cor-1 | F26H9.5.1 | R01H10.3c.2 | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Coronin-like protein cor-1; Required to direct the migration of Q neuroblasts along the anterior axis of the body during larval development. This is dependent on its asymmetric expression in Q neuroblasts. Belongs to the WD repeat coronin family. | 0.431 |