STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
attf-4AT hook-containing protein attf-4. (529 aa)    
Predicted Functional Partners:
C07H4.1
Uncharacterized protein.
      
 0.949
wht-1
ABC transporter ATP-binding protein/permease wht-1; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
   
  
 0.912
npp-14
Nuclear pore complex protein 14; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity). Plays a role in apoptosis by tethering caspase ced-3 to the nuclear membrane preventing its autoprocessing in absence of ced-4.
      
 0.698
C34F6.9
USP domain-containing protein; Belongs to the peptidase C19 family.
   
  
 0.619
klu-1
KLUmpfuss related.
      
 0.531
egl-5
Homeobox protein egl-5; Essential for the determination of specific neurons.
    
 
 0.473
mab-5
Homeobox protein mab-5; Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation. Belongs to the Antp homeobox family.
   
 
 0.471
oef-1
Oocyte Excluded Factor.
      
 0.467
rpc-1
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.463
dmd-4
DM domain-containing protein.
    
 
 0.458
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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