STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nas-7Zinc metalloproteinase nas-7; Metalloprotease. (382 aa)    
Predicted Functional Partners:
col-65
Col_cuticle_N domain-containing protein.
   
  
 0.801
elpc-4
Putative elongator complex protein 4; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs; Belongs to the ELP4 family.
      
 0.619
nhr-1
Nuclear hormone receptor family member nhr-1; Orphan nuclear receptor.
      
 0.531
nas-38
Zinc metalloproteinase nas-38; Metalloprotease.
  
  
0.496
nas-21
Zinc metalloproteinase-like protein nas-21; May lack metalloprotease activity.
  
   
0.491
nas-22
Zinc metalloproteinase nas-22; Metalloprotease.
  
  
0.471
F55G11.2
CUB_2 domain-containing protein.
      
 0.467
col-176
Col_cuticle_N domain-containing protein.
   
 
 0.454
suro-1
Putative carboxypeptidase suro-1; May play a role in processing or organization of cuticle collagen proteins, including rol-6 and col-19.
   
  
 0.403
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.