STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyk-7Cytokinesis defective protein 7. (267 aa)    
Predicted Functional Partners:
F30B5.4
Uncharacterized protein F30B5.4; Belongs to the OKL38 family.
   
  
 0.857
trcs-2
TRansport of membrane to Cell Surface.
   
  
 0.710
ani-2
Anillin-like protein 2; Required to maintain the structure of the rachis, the central cytoplasmic core of the syncytial adult gonad. Failure to maintain the rachis leads to premature dissociation of oocytes and thereby impedes oogenesis.
   
  
 0.704
pgl-1
Guanyl-specific ribonuclease pgl-1; Guanyl-specific endoribonuclease which cleaves the phosphodiester bond in single-stranded RNA between the 3'-guanylic residue and the 5'-OH residue of adjacent nucleotide, resulting in the formation of a corresponding 2',3'-cyclic phosphate intermediate. Together with the P-granule component pgl-3, is involved in the formation of P-granules. Together with pgl-3, probably recruits other granule components such as pos-1, mex-3 and glh-1 to P-granules. In addition, may act redundantly with pgl-3 to protect germ cells from excessive germline apoptosis du [...]
   
  
 0.674
unc-59
Septin-type G domain-containing protein.
   
  
 0.672
ptc-2
SSD domain-containing protein.
      
 0.667
cyk-4
CYtoKinesis defect.
   
  
 0.627
ani-1
Anillin-like protein 1; Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Pro [...]
   
  
 0.621
Y110A2AR.1
Receptor expression-enhancing protein.
   
    0.556
him-3
HORMA domain-containing protein.
   
    0.550
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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