STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vgln-1ViGiLN homolog. (1220 aa)    
Predicted Functional Partners:
rack-1
Guanine nucleotide-binding protein subunit beta-2-like 1; Required for the expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury.
   
 
 0.736
F41D9.2
DOMON domain-containing protein.
      
 0.660
Y73B6BL.31
TPT domain-containing protein.
      
 0.660
sec-61
Plug_translocon domain-containing protein.
   
  
 0.649
cgh-1
ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
   
 
 0.644
ain-2
ALG-1 INteracting protein.
   
 
 0.639
Y17G7B.20
Uncharacterized protein.
   
  
 0.619
Y106G6H.6
Uncharacterized protein.
      
 0.615
Y17G7B.18
Probable RNA methyltransferase Y17G7B.18; Probable RNA methyltransferase; Belongs to the methyltransferase superfamily.
      
 0.615
B0280.17
KH domain-containing protein.
      
 0.610
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.