STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zig-4Zwei Ig domain protein zig-4; Required for maintaining axon position of PVQ and PVP neurons postembryonically in the ventral nerve cord (VNC) by preventing axons drifting into the opposite side of the VNC that could occur during body growth and movement. (253 aa)    
Predicted Functional Partners:
dig-1
Mesocentin; Encodes an adhesion molecule involved in sensory map formation. Functions during sensory process development in the nervous system.
   
 
 0.859
lips-13
LIPaSe related.
      
 0.810
zig-8
Zwei Ig domain protein zig-8; Together with zig-5, required postembryonically to maintain the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP and HSN neurons by preventing their displacement that could occur during body growth and movement. May act by reducing L1CAM-like protein sax-7 (long isoform) adhesion.
   
  
 0.765
lips-11
LIPaSe related.
      
 0.759
F28H1.1
Uncharacterized protein.
   
  
 0.744
zig-7
Zwei Ig domain protein zig-7; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons.
      
 0.741
F13B12.4
Putative pyridoxal-phosphate dependent protein F13B12.4; Belongs to the cysteine synthase/cystathionine beta- synthase family. Highly divergent.
      
 0.740
sax-7
Fibronectin type-III domain-containing protein.
    
 
 0.712
nhx-3
Probable Na(+)/H(+) antiporter nhx-3; Plays a role in epithelial membrane transport processes.
      
 0.699
lips-12
LIPaSe related.
      
 0.695
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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