STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdl-2Histidine Decarboxyase Like. (611 aa)    
Predicted Functional Partners:
C05D2.8
Uncharacterized protein.
      
 0.812
spl-1
Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Essential for normal development, intestinal integrity, growth and reproduction.
      
 0.700
basl-1
BAS-Like.
   
  
0.636
irld-14
Insulin/EGF-Receptor L Domain protein.
   
    0.592
try-7
Peptidase S1 domain-containing protein.
  
 0.584
gln-2
Probable glutamine synthetase.
  
  
 0.583
mpz-4
PDZ domain-containing protein.
   
   0.578
F36D3.5
Uncharacterized protein.
   
  
 0.564
F01G10.5
Uncharacterized protein.
   
   0.561
M110.7
Uncharacterized NTE family protein M110.7.
   
 
 0.561
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.