STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
catp-3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1054 aa)    
Predicted Functional Partners:
nkb-3
Probable sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). Implicated in genomic response to various soil bacteria that affects fitness, lifespan and brood size.
   
 0.767
nkb-1
Sodium/potassium-transporting ATPase subunit beta-1; Non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). May also may function in the peptidic vesicle transport pathway from the endoplasmic reticulum for the defecation behaviors.
   
 0.753
nkb-2
Na+/K+ ATPase, Beta subunit.
   
 0.753
K08D8.5
CUB_2 domain-containing protein.
   
 
 0.722
Y42A5A.3
Uncharacterized protein.
   
  
 0.715
clec-67
C-type lectin domain-containing protein.
   
 
 0.714
oac-6
NRF domain-containing protein.
   
  
 0.711
C17H12.8
CUB_2 domain-containing protein.
   
  
 0.710
tcc-1
Transmembrane and Coiled-Coil protein.
   
 
 0.683
irg-4
CUB_2 domain-containing protein.
   
  
 0.681
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.