STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mct-6MFS domain-containing protein. (594 aa)    
Predicted Functional Partners:
thk-1
Thymidine kinase.
      
 0.758
ttc-4
TeTratriCopeptide repeat domain protein related.
    
 
 0.700
F25B5.6
Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
   
  
 0.697
E01A2.1
Aldo_ket_red domain-containing protein.
   
  
 0.672
snf-5
Sodium-dependent transporter snf-5; Sodium-dependent amino acid transporter that mediates the uptake of the L-enantiomers of various amino acids, including L-proline and L-methionine, and also of acidic amino acids such as L-glutamic acid and L-aspartic acid (Probable). May additionally have a role in potassium-dependent amino acid absorption. In response to the availability of amino acid nutrients, may play a role in dauer formation. May play a role in promoting fertility. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.667
slcf-1
SoLute Carrier Family.
      
 0.660
dld-1
Dihydrolipoyl dehydrogenase, mitochondrial.
   
  
 0.598
tkt-1
Transket_pyr domain-containing protein.
   
 
 0.574
eef-1B.1
Probable elongation factor 1-beta/1-delta 1; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP; Belongs to the EF-1-beta/EF-1-delta family.
      
 0.549
snf-1
Sodium: Neurotransmitter symporter Family.
   
  
 0.483
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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