STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erg-28Probable ergosterol biosynthetic protein 28 homolog; Promotes the translocation of slo-1 potassium ion channels from the endoplasmic reticulum to its final destination at the plasma membrane, probably by shielding from premature proteasomal degradation in the endoplasmic reticulum; Belongs to the ERG28 family. (162 aa)    
Predicted Functional Partners:
W08F4.3
Uncharacterized protein.
   
 
 0.986
dhcr-7
DeHydroCholesterol Reductase.
   
 
 0.976
Y46G5A.18
R3H-assoc domain-containing protein.
   
 
 0.974
agmo-1
Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily.
   
 
 0.973
B0334.5
Uncharacterized protein.
   
 
 0.951
hsd-2
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 
 0.930
F49E12.10
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.917
drd-1
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.905
Y52B11A.3
Uncharacterized protein.
   
  
 0.901
F35C8.5
Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase.
   
 
 0.875
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]