STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-22DeHydrogenases, Short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (333 aa)    
Predicted Functional Partners:
pks-1
PolyKetide Synthase.
  
 0.839
trpp-5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily.
   
  
 0.813
C01G10.7
HpcH_HpaI domain-containing protein.
   
 
 0.801
B0464.9
Probable protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated; Belongs to the AB hydrolase superfamily.
  
 0.761
B0491.1
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
   
  
 0.741
C24D10.4
Uncharacterized protein.
   
  
 0.732
K06H6.2
Methyltransf_21 domain-containing protein.
   
 
 0.728
T06D8.9
Uncharacterized protein.
   
 
 0.728
C35D10.10
Thioredoxin-related transmembrane protein 2 homolog.
   
  
 0.724
ZK1248.15
WW domain-containing protein.
   
 
 0.719
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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