STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C16C10.8Uncharacterized protein C16C10.8. (253 aa)    
Predicted Functional Partners:
Y48A6B.3
Putative H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
   
   0.912
Y54E10A.10
Ribosome production factor 2 homolog.
   
   0.912
B0511.6
RNA helicase.
   
 
 0.904
T23G7.3
G-patch domain-containing protein.
   
   0.902
rrp-1
Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA. Belongs to the RRP1 family.
   
 
 0.900
ZK546.14
Uncharacterized protein ZK546.14.
   
   0.895
rrbs-1
Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.892
nifk-1
RRM domain-containing protein.
   
 
 0.885
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
   0.879
K12H4.3
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
 
 0.856
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.