STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ins-11Probable insulin-like peptide gamma-type 1. (91 aa)    
Predicted Functional Partners:
ins-7
Probable insulin-like peptide beta-type 4.
   
  
 0.808
ins-23
Probable insulin-like peptide alpha-type 3.
   
  
 0.758
ins-20
INSulin related.
   
  
 0.746
ins-4
Probable insulin-like peptide beta-type 1; Probable insulin-like peptide which negatively regulates synapse development at the neuromuscular junctions. Probably acts as a daf-2/InsR agonist ligand to prevent dauer formation under optimal environmental conditions.
   
  
 0.705
ins-3
Probable insulin-like peptide beta-type 3.
      
 0.699
ins-13
INSulin related.
      
 0.694
ins-36
INSulin related.
      
 0.691
ins-26
INSulin related.
   
  
 0.670
ins-31
INSulin related.
      
 0.663
ins-18
INSulin related.
   
  
 0.661
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.