STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C25A1.1Nefa_Nip30_N domain-containing protein. (219 aa)    
Predicted Functional Partners:
ceh-45
Homeobox domain-containing protein.
    
   0.916
cdc-5L
Cell Division Cycle related.
   
   0.853
prp-8
Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
   
   0.848
syf-1
SYF pre-mRNA splicing factor homolog.
    
   0.845
Y66D12A.9
Uncharacterized protein.
   
 
 0.808
Y40D12A.1
Adrift-type SAM-dependent 2'-O-MTase domain-containing protein.
   
  
 0.691
rnp-4
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
   0.538
exos-4.2
RNase_PH domain-containing protein.
   
  
 0.538
camt-1
CAMTA (CAlModulin-binding Transcriptional activator).
    
 
 0.535
bud-31
Protein BUD31 homolog; Involved in pre-mRNA splicing process.
   
   0.528
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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