STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C27A12.2Suppressor of ZYg-1. (603 aa)    
Predicted Functional Partners:
ari-1.3
RBR-type E3 ubiquitin transferase.
   
 
 0.916
ari-1.2
RBR-type E3 ubiquitin transferase.
   
 
 0.822
ari-1.4
RBR-type E3 ubiquitin transferase.
   
 
 0.724
ari-1.1
RBR-type E3 ubiquitin transferase.
   
 
 0.679
msp-142
Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142.
    
 
 0.576
F44E2.7
Putative zinc finger protein F44E2.7.
   
   0.487
hmg-1.2
High mobility group protein 1.2.
   
 
 0.481
K02C4.3
Probable ubiquitin carboxyl-terminal hydrolase K02C4.3.
   
   0.476
drsh-1
Ribonuclease 3; Executes the initial step of microRNA (miRNA) processing in the nucleus, that is the cleavage of pri-miRNA to release pre-miRNA. Involved in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in fertility. Required for the function or synthesis of the let-7 miRNA. Belongs to the ribonuclease III family.
   
 
 0.450
uri-1
URI (Unconventional prefoldin RPB5 Interactor) homolog.
   
    0.434
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.