STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fkh-3Fork-head domain-containing protein. (421 aa)    
Predicted Functional Partners:
fkh-4
Fork-head domain-containing protein.
   
  
0.955
fkh-10
Fork-head domain-containing protein.
   
 
 0.791
fkh-7
Fork-head domain-containing protein.
    
 
 0.775
fkh-9
Fork-head domain-containing protein.
      
 0.758
C10G8.8
Uncharacterized protein.
      
 0.660
pha-4
Defective pharyngeal development protein 4; Acts as a transcription factor required for formation of the pharyngeal primordium. Binds to the consensus sequence 5'-T[AG]TT[TG][AG][TC]-3' with variations of the sequence affecting onset of target gene expression. Activates a wide array of pharyngeal genes including ceh-22 and myo-2 and represses ectodermal genes lin-26 and elt-3, ensuring pharyngeal cell fate. Required for recruitment of htz-1 to a subset of pharyngeal promoters to ensure gene activation and also acts synergistically with tbx-2 in pharyngeal development. Acts in the regul [...]
    
 
 0.604
pes-1
Fork-head domain-containing protein.
   
  
 0.568
lin-31
Protein lin-31; Lin-31 regulates how vulval precursor cells choose their fate. It helps specify three alternative cell fates in vulval development.
   
  
 0.542
T25E12.6
FTH domain-containing protein.
   
    0.538
ZK177.1
Uncharacterized protein ZK177.1.
   
    0.538
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.