STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
snb-5Synaptobrevin-like protein 5. (102 aa)    
Predicted Functional Partners:
unc-64
Syntaxin-1A homolog; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the qui [...]
   
 0.941
snap-1
SNAP (Soluble NSF Attachment Protein) homolog.
   
 0.931
snb-6
V-SNARE coiled-coil homology domain-containing protein.
   
 
 
0.917
snb-7
V-SNARE coiled-coil homology domain-containing protein.
  
 
 
0.903
ric-4
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 0.857
vti-1
t-SNARE coiled-coil homology domain-containing protein.
   
 0.856
syx-6
Putative syntaxin 6; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family.
    
 0.850
snt-1
Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death.
   
 0.838
syx-7
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
   
 0.816
syx-5
Putative syntaxin-5; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family.
    
 0.815
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.