STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mks-2MecKel-Gruber Syndrome (MKS) homolog. (142 aa)    
Predicted Functional Partners:
mks-3
MecKel-Gruber Syndrome (MKS) homolog.
   
  
 0.899
mks-6
C2 domain-containing protein.
   
  
 0.899
mksr-1
MecKel Syndrome 1 (MKS1)-Related.
   
  
 0.888
mks-1
MecKel-Gruber Syndrome (MKS) homolog.
   
  
 0.822
nphp-4
NePHronoPhthisis (Human kidney disease) homolog.
   
  
 0.811
tmem-17
TMEM (Human TransMEMbrane protein) homolog.
   
  
 0.775
arl-6
ADP-ribosylation factor-like protein 6; Belongs to the small GTPase superfamily. Arf family.
   
  
 0.751
dyf-6
Intraflagellar transport protein 46 homolog; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for normal morphology and function of ciliated amphid sensory neurons.
   
  
 0.739
mks-5
Protein fantom; Thought to have an important role in cilia formation and cilia-mediated chemosensation. Involved in the docking of other MKS/MKSR proteins localized to the transition zone of the cilia. Belongs to the RPGRIP1 family.
   
  
 0.738
mksr-2
MecKel Syndrome 1 (MKS1)-Related.
   
  
 0.736
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.