node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C30F12.2 | F56C9.10 | C30F12.2.2 | F56C9.10b.1 | Uncharacterized protein. | Uncharacterized protein. | 0.402 |
C30F12.2 | alh-13 | C30F12.2.2 | T22H6.2b.1 | Uncharacterized protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.672 |
C30F12.2 | cdc-48.1 | C30F12.2.2 | C06A1.1.1 | Uncharacterized protein. | Transitional endoplasmic reticulum ATPase homolog 1; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. Can also prevent aggregation of unfolded proteins also in an ATP- independent manner. Targets polyubiquitinated proteins for proteasomal degradation by binding to 'Lys-48'-linked polyubiquitin chains. Involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents the act [...] | 0.421 |
C30F12.2 | cdc-48.3 | C30F12.2.2 | K04G2.3.1 | Uncharacterized protein. | ATPase family protein 2 homolog; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (By similarity). Required for various steps of embryonic mitosis including centrosome duplication, spindle assembly, ER dynamics and cell cycle progression. Regulates the stability and activity of kinase air-2, a component of the chromosomal passenger complex (CPC). Inhibits air-2 kinase activity from metaphase to late telophase and negatively regulates air-2 stability during mitotic exit. Controls ER transition into she [...] | 0.402 |
C30F12.2 | dhhc-13 | C30F12.2.2 | H32C10.3.1 | Uncharacterized protein. | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. | 0.425 |
C30F12.2 | dpm-1 | C30F12.2.2 | Y66H1A.2a.1 | Uncharacterized protein. | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | 0.456 |
C30F12.2 | mev-1 | C30F12.2.2 | T07C4.7a.2 | Uncharacterized protein. | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. | 0.678 |
C30F12.2 | mrps-9 | C30F12.2.2 | F09G8.3.1 | Uncharacterized protein. | Probable 40S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. | 0.486 |
C30F12.2 | pfas-1 | C30F12.2.2 | F10F2.2.1 | Uncharacterized protein. | Probable phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity); In the N-terminal section; belongs to the FGAMS family. | 0.443 |
C30F12.2 | taco-1 | C30F12.2.2 | Y50D7A.9.1 | Uncharacterized protein. | Translational Activator of Cytochrome c Oxidase. | 0.437 |
F56C9.10 | C30F12.2 | F56C9.10b.1 | C30F12.2.2 | Uncharacterized protein. | Uncharacterized protein. | 0.402 |
alh-13 | C30F12.2 | T22H6.2b.1 | C30F12.2.2 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Uncharacterized protein. | 0.672 |
cdc-48.1 | C30F12.2 | C06A1.1.1 | C30F12.2.2 | Transitional endoplasmic reticulum ATPase homolog 1; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. Can also prevent aggregation of unfolded proteins also in an ATP- independent manner. Targets polyubiquitinated proteins for proteasomal degradation by binding to 'Lys-48'-linked polyubiquitin chains. Involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents the act [...] | Uncharacterized protein. | 0.421 |
cdc-48.1 | cdc-48.3 | C06A1.1.1 | K04G2.3.1 | Transitional endoplasmic reticulum ATPase homolog 1; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. Can also prevent aggregation of unfolded proteins also in an ATP- independent manner. Targets polyubiquitinated proteins for proteasomal degradation by binding to 'Lys-48'-linked polyubiquitin chains. Involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents the act [...] | ATPase family protein 2 homolog; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (By similarity). Required for various steps of embryonic mitosis including centrosome duplication, spindle assembly, ER dynamics and cell cycle progression. Regulates the stability and activity of kinase air-2, a component of the chromosomal passenger complex (CPC). Inhibits air-2 kinase activity from metaphase to late telophase and negatively regulates air-2 stability during mitotic exit. Controls ER transition into she [...] | 0.929 |
cdc-48.3 | C30F12.2 | K04G2.3.1 | C30F12.2.2 | ATPase family protein 2 homolog; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (By similarity). Required for various steps of embryonic mitosis including centrosome duplication, spindle assembly, ER dynamics and cell cycle progression. Regulates the stability and activity of kinase air-2, a component of the chromosomal passenger complex (CPC). Inhibits air-2 kinase activity from metaphase to late telophase and negatively regulates air-2 stability during mitotic exit. Controls ER transition into she [...] | Uncharacterized protein. | 0.402 |
cdc-48.3 | cdc-48.1 | K04G2.3.1 | C06A1.1.1 | ATPase family protein 2 homolog; ATP-dependent chaperone which uses the energy provided by ATP hydrolysis to generate mechanical force to disassemble protein complexes (By similarity). Required for various steps of embryonic mitosis including centrosome duplication, spindle assembly, ER dynamics and cell cycle progression. Regulates the stability and activity of kinase air-2, a component of the chromosomal passenger complex (CPC). Inhibits air-2 kinase activity from metaphase to late telophase and negatively regulates air-2 stability during mitotic exit. Controls ER transition into she [...] | Transitional endoplasmic reticulum ATPase homolog 1; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. Can also prevent aggregation of unfolded proteins also in an ATP- independent manner. Targets polyubiquitinated proteins for proteasomal degradation by binding to 'Lys-48'-linked polyubiquitin chains. Involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents the act [...] | 0.929 |
dhhc-13 | C30F12.2 | H32C10.3.1 | C30F12.2.2 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. | Uncharacterized protein. | 0.425 |
dpm-1 | C30F12.2 | Y66H1A.2a.1 | C30F12.2.2 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. | Uncharacterized protein. | 0.456 |
mev-1 | C30F12.2 | T07C4.7a.2 | C30F12.2.2 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. | Uncharacterized protein. | 0.678 |
mev-1 | mrps-9 | T07C4.7a.2 | F09G8.3.1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. | Probable 40S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. | 0.433 |