STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
efr-3Protein EFR3 homolog; Belongs to the EFR3 family. (859 aa)    
Predicted Functional Partners:
ttc-7
TPR_REGION domain-containing protein.
   
 
 0.946
F56A11.6
Uncharacterized protein.
   
  
 0.812
C32D5.12
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
      
 0.809
K11H12.3
Uncharacterized protein.
      
 0.809
cutl-28
CUTiclin-Like.
      
 0.806
C32D5.10
Uncharacterized RING finger protein C32D5.10.
   
  
 0.743
Y75B8A.24
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.722
C32D5.8
Thioredoxin domain-containing protein.
      
 0.698
rpl-15
60S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
      
 0.660
cblc-1
MMACHC-like protein; Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate. Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione- dependent reductive demethylation of adenosylcobalamin. Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen. Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives; [...]
 
 
  
 0.584
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.