STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vet-2Very Early Transcript. (785 aa)    
Predicted Functional Partners:
sig-7
Peptidyl-prolyl cis-trans isomerase sig-7; Probable PPIase that accelerates the folding of proteins (By similarity). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans- splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transc [...]
   
  
 0.854
fkh-4
Fork-head domain-containing protein.
   
    0.839
sdz-27
SKN-1 Dependent Zygotic transcript.
   
  
 0.813
sdz-28
SKN-1 Dependent Zygotic transcript.
   
  
 0.783
vet-6
Very Early Transcript.
   
  
0.738
sqd-1
Homologous to Drosophila SQD (Squid) protein.
      
 0.698
sepa-1
Protein sepa-1; Adapter protein that connects P-granules in somatic cells with the autophagic machinery. Association with other adapters such as epg-2 and P-granule components such as pgl-3 is required for the accumulation and degradation of P-granules by autophagy in somatic cells. This ensures exclusive localization of the P-granules in germ cells.
   
  
0.673
athp-3
PHD domain-containing protein.
   
    0.637
vet-1
Very Early Transcript.
   
    0.615
dsl-2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
    0.615
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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