Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| R166.3 | memo-1 | R166.3.1 | C37C3.8c.1 | Uncharacterized protein R166.3. | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.676 |
| ZK686.3 | memo-1 | ZK686.3.1 | C37C3.8c.1 | Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation acro [...] | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.657 |
| bli-3 | doxa-1 | F56C11.1.1 | C06E1.3.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | 0.970 |
| bli-3 | memo-1 | F56C11.1.1 | C37C3.8c.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.805 |
| bli-3 | rho-1 | F56C11.1.1 | Y51H4A.3a.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.532 |
| btb-14 | memo-1 | Y57A10B.3.1 | C37C3.8c.1 | BTB/POZ domain-containing protein Y57A10B.3. | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.662 |
| btb-14 | shc-2 | Y57A10B.3.1 | T27F7.2a.1 | BTB/POZ domain-containing protein Y57A10B.3. | SH2 domain-containing protein. | 0.422 |
| doxa-1 | bli-3 | C06E1.3.1 | F56C11.1.1 | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | 0.970 |
| doxa-1 | memo-1 | C06E1.3.1 | C37C3.8c.1 | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.667 |
| doxa-1 | shc-2 | C06E1.3.1 | T27F7.2a.1 | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | SH2 domain-containing protein. | 0.661 |
| hsp-12.1 | memo-1 | T22A3.2b.1 | C37C3.8c.1 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.557 |
| kmo-1 | memo-1 | R07B7.5.1 | C37C3.8c.1 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | 0.553 |
| memo-1 | R166.3 | C37C3.8c.1 | R166.3.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Uncharacterized protein R166.3. | 0.676 |
| memo-1 | ZK686.3 | C37C3.8c.1 | ZK686.3.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation acro [...] | 0.657 |
| memo-1 | bli-3 | C37C3.8c.1 | F56C11.1.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | 0.805 |
| memo-1 | btb-14 | C37C3.8c.1 | Y57A10B.3.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | BTB/POZ domain-containing protein Y57A10B.3. | 0.662 |
| memo-1 | doxa-1 | C37C3.8c.1 | C06E1.3.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | 0.667 |
| memo-1 | hsp-12.1 | C37C3.8c.1 | T22A3.2b.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. | 0.557 |
| memo-1 | kmo-1 | C37C3.8c.1 | R07B7.5.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.553 |
| memo-1 | rho-1 | C37C3.8c.1 | Y51H4A.3a.1 | Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family. | Ras-like GTP-binding protein rhoA; Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation. Also required for ventral migration of P cells during larval development. Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development. In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology. In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89. Ass [...] | 0.728 |
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