STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C39H7.4Uncharacterized protein. (391 aa)    
Predicted Functional Partners:
srw-17
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.910
nhr-122
Nuclear Hormone Receptor family.
      
 0.910
hpo-15
Amino_oxidase domain-containing protein.
   
  
 0.896
nep-17
NEPrilysin metallopeptidase family.
   
  
 0.838
asah-1
Acid ceramidase subunit alpha; Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH.
   
  
 0.686
adr-2
Double-stranded RNA-specific adenosine deaminase adr-2; Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. Acts primarily on non-coding regions of protein- coding genes including introns and untranslated regions (UTR). Required for normal chemotaxis. Edits the 3' UTR of clec-41 which is required for normal clec-41 expression and for chemotaxis. Plays a role in determining lifespan. Not required for RNA interference. Likely to play a role in determining whether a dsRNA enters the RNAi pathway.
      
 0.660
Y75B8A.8
Uncharacterized protein.
      
 0.616
W07G4.3
SCY1 Like pseudokinase.
      
 0.586
adbp-1
Adr-2-binding protein 1; Required for the A-I editing activity of the double-stranded RNA-specific adenosine deaminase adr-2 by facilitating adr-2 nuclear localization.
      
 0.461
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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