STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
elo-4Putative fatty acid elongation protein 4; Could be implicated in synthesis of very long chain fatty acids; Belongs to the ELO family. (291 aa)    
Predicted Functional Partners:
K03H1.13
Fucokinase domain-containing protein.
      
 0.806
ceeh-2
Epoxide hydrolase 2; Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against trans-1,3-diphenylpropene oxide (t-DPPO), epoxyeicosatrienoic acids (EETs) including 8,9-EET, 11,12-EET and 14,15-EET and the linoleic acid metabolites 12,13-epoxy-9-octadecenoate (12,13-EpOME) and 9,10-epoxy-12-octadecenoate (9,10-EpOME). Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
      
 0.758
K07E8.7
Uncharacterized protein K07E8.7; Belongs to the pseudouridine synthase RluA family.
      
 0.700
stdh-1
Putative steroid dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
     
  0.698
stdh-3
Putative steroid dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
     
  0.698
let-767
Very-long-chain 3-oxooacyl-coA reductase let-767; Required for branched chain fatty acid synthesis. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. Very long-chain fatty acids (VLCFAs) serve as precursors for ceramide and sphingolipids. May also be required for sterol hormone production; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
     
  0.698
stdh-2
Putative steroid dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
     
  0.698
stdh-4
Putative steroid dehydrogenase 4; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
     
  0.698
drl-1
Protein drl-1; Negatively regulates lifespan and health span probably by participating in nutrient sensing.
      
 0.697
elo-8
Elongation of very long chain fatty acids protein.
      
 0.697
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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