STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C44B11.1Uncharacterized protein. (190 aa)    
Predicted Functional Partners:
algn-2
Asparagine Linked Glycosylation (ALG) homolog, Nematode.
      
 0.918
rpl-7A
60S ribosomal protein L7a; Belongs to the eukaryotic ribosomal protein eL8 family.
      
 0.818
zip-1
BZIP transcription factor family.
      
 0.699
smg-2
Regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an smg-2-3-4 surveillance complex is believed to activate NMD (By similarity).
      
 0.691
fah-1
Fumarylacetoacetase.
 
      0.689
kap-1
Kinesin-Associated Protein.
   
    0.585
eef-1G
Probable elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
      
 0.546
pyk-1
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.477
pyk-2
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.477
yars-1
Tyrosine--tRNA ligase.
      
 0.468
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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