STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C44E12.1M20_dimer domain-containing protein. (351 aa)    
Predicted Functional Partners:
cpin-1
Amidohydro-rel domain-containing protein.
 
  
 0.903
R08E5.1
Methyltranfer_dom domain-containing protein.
     
 0.883
T05E7.1
Uncharacterized protein.
  
  
 0.860
zmp-2
Matrix metalloproteinase-B; Metalloprotease involved in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Plays a role in thermotolerance probably by preventing the accumulation of oxidized lipoproteins and cholesterol.
   
  
 0.806
alh-13
Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.794
K12H4.7
Putative serine protease K12H4.7.
   
  
 0.745
his-20
Histone H2B 2.
      
 0.690
suox-1
Cytochrome b5 heme-binding domain-containing protein.
     
 0.680
col-79
Putative cuticle collagen 79; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
      
 0.668
mpst-3
MercaptoPyruvate SulfurTransferase homolog.
  
  
 0.668
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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