STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C47E8.4Protein FAM50 homolog; Belongs to the FAM50 family. (326 aa)    
Predicted Functional Partners:
K07C5.6
Pre-mRNA-splicing factor SLU7; Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Belongs to the SLU7 family.
   
 
  0.872
let-504
Nkap_C domain-containing protein.
   
 
  0.835
smg-4
Smg4_UPF3 domain-containing protein.
   
  0.832
T23G11.4
Uncharacterized protein.
   
 0.830
F53F4.14
Sde2_N_Ubi domain-containing protein.
   
 
 0.821
F37A4.2
Uncharacterized protein F37A4.2.
   
 
 0.820
Y69A2AR.21
Uncharacterized protein.
   
 
 0.818
cyn-10
Peptidyl-prolyl cis-trans isomerase 10; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
  0.815
Y66D12A.8
Uncharacterized protein.
   
 
  0.814
aly-3
FoP_duplication domain-containing protein.
   
  0.813
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.