STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gasr-8GAS (Human Growth Arrest-Specific) Related. (410 aa)    
Predicted Functional Partners:
K10G6.4
Uncharacterized protein.
   
  
 0.901
dyf-19
Uncharacterized protein.
   
  
 0.891
Y57G11C.32
Uncharacterized protein.
   
  
 0.821
set-5
SET domain-containing protein.
      
 0.808
grdn-1
Girdin homolog; Scaffolding protein that plays a role in ciliogenesis, cilium positioning and dendrite anchoring in sensory amphid neurons including AWB, AWA, AWC, ADL and ASI and the phasmid neurons PHA and PHB. Its role in cilium positioning may be through regulation of the localization of cell adhesion proteins such as the apical junction protein ajm-1, and the ciliary scaffolding protein Rootletin/che-10. Belongs to the CCDC88 family.
      
 0.758
arl-13
ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. Required for normal sensory cilium function. May act by maintaining the association between IFT subcomplexes A and B; Belongs to the small GTPase superfamily. Arf family.
   
  
 0.706
hyls-1
Hydrolethalus syndrome protein 1 homolog; Plays an important role ciliogenesis. Belongs to the HYLS1 family.
      
 0.693
tbb-4
Tubulin beta-4 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
   
  
 0.673
dyf-18
Protein kinase domain-containing protein.
   
  
 0.634
kap-1
Kinesin-Associated Protein.
   
  
 0.541
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.