STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C50F4.12Uncharacterized protein. (439 aa)    
Predicted Functional Partners:
fzo-1
Transmembrane GTPase fzo-1; Probable transmembrane GTPase (By similarity). Mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
   
 
 0.809
C06G3.6
ZZ-type domain-containing protein.
     
  0.800
vdac-1
Probable voltage-dependent anion-selective channel; Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.
     
  0.800
ruvb-1
RuvB-like 1; Possesses single-stranded DNA-stimulated ATPase and ATP dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). May participate in several chromatin remodeling complexes that mediate the ATP-dependent exchange of histones and remodel chromatin by shifting nucleosomes (By similarity). Involvement in these complexes is likely required for transcriptional activation of selected genes and DNA repair in response to DNA damage (By similarity). Involved in the Ce- Tor signaling pathway whereby it i [...]
 
 
    0.719
mrpl-36
Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.
    
 
 0.681
rpom-1
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.654
rpl-25.2
60S ribosomal protein L23a 2; This protein binds to a specific region on the 26S rRNA.
    
   0.637
rpl-25.1
60S ribosomal protein L23a 1; This protein binds to a specific region on the 26S rRNA.
    
   0.637
rpl-4
60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
    
   0.632
rps-16
40S ribosomal protein S16.
    
   0.632
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.