STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C52E12.1RING-type domain-containing protein. (925 aa)    
Predicted Functional Partners:
rps-10
S10_plectin domain-containing protein.
    
 
 0.958
rps-20
Ribosomal_S10 domain-containing protein.
    
 
 0.948
rps-3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
 
 0.927
rack-1
Guanine nucleotide-binding protein subunit beta-2-like 1; Required for the expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury.
    
 
 0.814
gcn-1
TOG domain-containing protein.
    
 
 0.801
abce-1
ABC transporter, class E.
   
  
 0.776
xrn-1
5'-3' exoribonuclease 1.
      
 0.749
mrrf-1
Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity); Belongs to the RRF family.
      
 0.722
Y54E10A.11
E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to vcp/p97 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family.
   
 
 0.700
Y82E9BR.18
Uncharacterized protein.
   
  
 0.689
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (22%) [HD]