node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T08A11.1 | cnt-2 | T08A11.1.1 | Y39A1A.15a.1 | DEP domain-containing protein. | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | 0.745 |
T08A11.1 | grp-1 | T08A11.1.1 | K06H7.4.1 | DEP domain-containing protein. | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | 0.612 |
T08A11.1 | ham-1 | T08A11.1.1 | F53B2.6.1 | DEP domain-containing protein. | Stork_head domain-containing protein. | 0.616 |
T08A11.1 | pig-1 | T08A11.1.1 | W03G1.6c.1 | DEP domain-containing protein. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.480 |
T08A11.1 | toe-2 | T08A11.1.1 | C56E6.3a.1 | DEP domain-containing protein. | Target Of ERK kinase MPK-1. | 0.920 |
cnt-2 | T08A11.1 | Y39A1A.15a.1 | T08A11.1.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | DEP domain-containing protein. | 0.745 |
cnt-2 | grp-1 | Y39A1A.15a.1 | K06H7.4.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | 0.463 |
cnt-2 | ham-1 | Y39A1A.15a.1 | F53B2.6.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | Stork_head domain-containing protein. | 0.709 |
cnt-2 | pig-1 | Y39A1A.15a.1 | W03G1.6c.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.721 |
cnt-2 | toe-2 | Y39A1A.15a.1 | C56E6.3a.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | Target Of ERK kinase MPK-1. | 0.759 |
grp-1 | T08A11.1 | K06H7.4.1 | T08A11.1.1 | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | DEP domain-containing protein. | 0.612 |
grp-1 | cnt-2 | K06H7.4.1 | Y39A1A.15a.1 | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | 0.463 |
grp-1 | pig-1 | K06H7.4.1 | W03G1.6c.1 | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.570 |
grp-1 | toe-2 | K06H7.4.1 | C56E6.3a.1 | GTP exchange factor for ARFs 1; Promotes guanine-nucleotide exchange on ARF. Promotes the activation of ARF through replacement of GDP with GTP (By similarity). Plays a role in cell shedding during embryogenesis, probably by promoting the endocytosis of cell adhesion molecules. | Target Of ERK kinase MPK-1. | 0.688 |
ham-1 | T08A11.1 | F53B2.6.1 | T08A11.1.1 | Stork_head domain-containing protein. | DEP domain-containing protein. | 0.616 |
ham-1 | cnt-2 | F53B2.6.1 | Y39A1A.15a.1 | Stork_head domain-containing protein. | Arf-GAP with ANK repeat and PH domain-containing protein cnt-2; GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; Belongs to the centaurin gamma-like family. | 0.709 |
ham-1 | pig-1 | F53B2.6.1 | W03G1.6c.1 | Stork_head domain-containing protein. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.806 |
ham-1 | toe-2 | F53B2.6.1 | C56E6.3a.1 | Stork_head domain-containing protein. | Target Of ERK kinase MPK-1. | 0.669 |
hcp-6 | pig-1 | Y110A7A.1b.1 | W03G1.6c.1 | Condensin-2 complex subunit. | Maternal embryonic leucine zipper kinase; Serine/threonine-protein kinase involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell by controlling spindle positioning, myosin distribution and the segregation of cell fate determinants. Promotes cell shedding during embryogenesis, probably through the endocytosis-mediated removal of cell adhesion molecules such as hmp-1 from the cell surface. May act downstream of par-4/strd-1/mop-25 to regulate cell shedding. | 0.528 |
hcp-6 | toe-2 | Y110A7A.1b.1 | C56E6.3a.1 | Condensin-2 complex subunit. | Target Of ERK kinase MPK-1. | 0.424 |