STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D1025.1Uncharacterized protein. (358 aa)    
Predicted Functional Partners:
K10D3.4
Uncharacterized protein.
      
 0.851
hmg-1.1
HMG box domain-containing protein.
      
 0.818
skn-1
Protein skinhead-1; Transcription factor required to specify the fate of ventral blastomeres in the early embryo, and postembryonically for the development of the intestine. Directly regulates expression of zygotically expressed med-1 and med-2 to direct mesendoderm development. Required for stl-1 mRNA up- regulation in response to oxidative stress and anoxia. Required for the up-regulation of gcs-1 and several glutathione-S-transferase mRNAs in response to oxidative stress generated during pathogenic bacterial infection. In neurons, involved in mitochondrial fusion and behavioral reco [...]
   
 
 0.590
C52A10.2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
      
 0.544
pgam-5
Serine/threonine-protein phosphatase Pgam5, mitochondrial; Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity (By similarity). Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
      
 0.543
Y42G9A.3
Uncharacterized protein.
      
 0.537
R05G9R.1
Uncharacterized protein.
      
 0.535
mxl-3
BHLH domain-containing protein.
      
 0.532
R01E6.5
Uncharacterized protein.
      
 0.532
tyr-5
Tyrosinase_Cu-bd domain-containing protein.
      
 0.465
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.