STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2005.3Uncharacterized protein D2005.3; Belongs to the PDCD5 family. (130 aa)    
Predicted Functional Partners:
rps-19
40S ribosomal protein S19; Belongs to the eukaryotic ribosomal protein eS19 family.
  
    0.916
rps-28
40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
  
    0.889
rps-11
Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family.
   
    0.888
rpl-35
60S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family.
   
    0.885
rpl-23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
   
  
 0.881
rps-3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
    0.879
rpl-34
Ribosomal Protein, Large subunit.
   
    0.868
rps-22
Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS8 family.
   
    0.844
pfd-1
Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family.
   
    0.823
rps-6
40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity). Negatively regulates lifespan ; Belongs to the eukaryotic ribosomal protein eS6 family.
   
    0.818
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.