STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E02C12.10CHK domain-containing protein. (417 aa)    
Predicted Functional Partners:
ZK507.1
Putative serine/threonine-protein kinase ZK507.1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
      
 0.967
gcy-11
Receptor-type guanylate cyclase gcy-11; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
      
 0.816
C18G1.8
Uncharacterized protein.
      
 0.809
F53E10.1
MOSC domain-containing protein.
      
 0.809
T22F3.2
USP domain-containing protein.
      
 0.809
str-200
Seven TM Receptor.
   
  
 0.762
M162.7
WSN domain-containing protein.
      
 0.697
sto-5
PHB domain-containing protein.
      
 0.667
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.