STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpf-4Peptidase_S9 domain-containing protein. (643 aa)    
Predicted Functional Partners:
rtfo-1
RNA polymerase-associated protein RTF1 homolog; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
   
  
 0.615
isw-1
Chromatin-remodeling complex ATPase chain isw-1; Energy-transducing component of a NURF-like (nucleosome- remodeling factor-like) complex, which would catalyze ATP-dependent nucleosome sliding and facilitate transcription of chromatin (Probable). Involved in vulval cell fates. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
   
   0.609
prp-38
Yeast PRP (Splicing factor) related.
   
  
 0.608
elpc-1
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.
   
    0.604
F23H11.2
TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
   
    0.601
F33A8.4
Uncharacterized protein.
   
    0.599
F58B3.4
NUC153 domain-containing protein.
   
    0.597
mrpl-38
Mitochondrial Ribosomal Protein, Large.
   
    0.596
fars-3
Phenylalanine--tRNA ligase beta subunit.
   
    0.592
F52C9.3
Uncharacterized protein F52C9.3.
   
    0.592
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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