STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flr-1FLR-1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (638 aa)    
Predicted Functional Partners:
ghi-1
Glycoprotein Hormone (FLR-2) Interacting protein.
   
  
 0.890
flr-4
Serine/threonine-protein kinase flr-4; Probable serine-threonine protein kinase involved in the control of defecation rhythms. Required to increase the length of defecation cycle period. Acts in a cell-functional rather than developmental aspect in the regulation of defecation rhythms.
   
  
 0.853
egas-4
EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.697
egas-3
EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.697
flr-2
CTCK domain-containing protein.
      
 0.692
pbo-1
Uncharacterized protein.
   
  
 0.678
egas-1
EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.660
vha-5
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.641
del-10
Degenerin-like protein del-10.
   
 
 0.621
acd-5
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
 
0.609
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.