STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcyt-1Putative choline-phosphate cytidylyltransferase; Belongs to the cytidylyltransferase family. (362 aa)    
Predicted Functional Partners:
pmt-2
Phosphoethanolamine MethylTransferase.
  
 
 0.990
ckb-1
Choline kinase B1; Belongs to the choline/ethanolamine kinase family.
   
 
 0.981
cept-1
Choline/EthanolaminePhosphoTransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.950
ckb-2
Choline kinase B2; Catalyzes the first step in phosphatidylcholine biosynthesis. Phosphorylates choline.
   
 
 0.947
ckb-3
Putative choline kinase B3; Belongs to the choline/ethanolamine kinase family.
     
 0.946
cka-2
Choline kinase A2; Catalyzes the first step in phosphatidylcholine biosynthesis. May contribute to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine but the activity is much higher with choline. Belongs to the choline/ethanolamine kinase family.
     
 0.946
pmt-1
Methyltransf_11 domain-containing protein.
  
 
 0.929
cept-2
Choline/EthanolaminePhosphoTransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.888
sams-1
Probable S-adenosylmethionine synthase 1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family.
   
  
 0.820
Y18H1A.11
CTP_transf_like domain-containing protein.
  
  
 
0.804
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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