STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F08D12.7Uncharacterized protein. (336 aa)    
Predicted Functional Partners:
C18B12.6
Uncharacterized protein.
      
 0.850
M60.6
Uncharacterized protein.
      
 0.850
erv-46
Yeast ERV (ER to Golgi transport Vesicle protein) homolog.
      
 0.812
R02E4.1
Uncharacterized protein.
      
 0.810
rbc-1
WD_REPEATS_REGION domain-containing protein.
      
 0.805
sgcb-1
SarcoGlyCan Beta homolog.
   
  
 0.744
dhs-5
Uncharacterized oxidoreductase dhs-5.
      
 0.699
rev-1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
      
 0.668
npr-10
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.665
twk-23
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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