STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F08G12.1Uncharacterized protein. (635 aa)    
Predicted Functional Partners:
trpp-3
Trafficking protein particle complex subunit 3 homolog; May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). Required for the systemic spread of the RNAi response ; Belongs to the TRAPP small subunits family. BET3 subfamily.
   
 
 0.782
F13E6.1
Uncharacterized protein F13E6.1; Belongs to the TPD52 family.
   
  
 0.776
W08E12.7
Peptidase_M24 domain-containing protein.
      
 0.758
Y38H6C.16
Uncharacterized protein.
      
 0.758
ZK1058.9
Uncharacterized protein.
      
 0.758
ccdc-47
CCDC (Human Coiled Coil Domain Containing) homolog.
   
 
 0.751
trpp-8
TRansport Protein Particle.
    
 
 0.749
nduo-4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
 
 0.748
gdi-1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 
 0.748
trpp-1
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
    
 
 0.740
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.