STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acl-13PlsC domain-containing protein. (363 aa)    
Predicted Functional Partners:
wht-5
ABC transporter domain-containing protein.
   
  
 0.890
acl-11
PlsC domain-containing protein.
      
 0.853
F57F4.1
Uncharacterized protein.
  
  
 0.835
elo-7
Elongation of very long chain fatty acids protein.
   
  
 0.795
acl-4
PlsC domain-containing protein.
      
 0.774
elo-8
Elongation of very long chain fatty acids protein.
   
  
 0.760
ech-7
Enoyl-CoA Hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
 0.684
gska-3
Protein kinase domain-containing protein.
   
 0.675
lbp-7
Fatty acid-binding protein homolog 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.660
rhy-1
Regulator of hypoxia-inducible factor 1; Involved in the response to variation in environmental oxygen levels by inhibiting hif-1-mediated gene transcription in a vhl-1- independent manner. Plays a role in susceptibility to killing mediated by P.aeruginosa and by pore-forming toxins produced by B.thuringiensis. Probably by preventing hif-1 transcriptional activity, regulates behavioral responses, such as locomotion speed following acute reoxygenation. Plays a role in normal egg-laying probably by regulating spermatogenesis and in body morphogenesis.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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