Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ZK430.5 | coh-3 | ZK430.5.1 | F08H9.1.1 | Peptidase C50 domain-containing protein. | Rad21_Rec8 domain-containing protein. | 0.806 |
| ZK430.5 | him-3 | ZK430.5.1 | ZK381.1a.2 | Peptidase C50 domain-containing protein. | HORMA domain-containing protein. | 0.454 |
| ZK430.5 | htp-1 | ZK430.5.1 | F41H10.10.1 | Peptidase C50 domain-containing protein. | HORMA domain-containing protein. | 0.458 |
| ZK430.5 | lab-1 | ZK430.5.1 | C03D6.6.1 | Peptidase C50 domain-containing protein. | Long arms of the bivalent protein 1; Involved in sister chromatid cohesion during mitosis and meiosis. In association with the gsp-2 phosphatase, it both restricts the localization and antagonizes the function of the air-2 kinase during meiosis I and mitosis to promote chromatid cohesion and spindle attachment. This in turn, drives germ cell immortality. Furthermore, may play a role in ensuring the timely assembly of the synaptonemal complex during prophase I of meiosis. | 0.660 |
| ZK430.5 | rad-51 | ZK430.5.1 | Y43C5A.6a.1 | Peptidase C50 domain-containing protein. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.466 |
| ZK430.5 | rec-8 | ZK430.5.1 | W02A2.6a.1 | Peptidase C50 domain-containing protein. | Meiotic recombination protein rec-8; Plays a role in meiotic chromosome cohesion and segregation. Necessary for sister chromatid co- orientation and sister chromatid cohension until meiosis II. May also be required for repair of programmed meiotic double stranded breaks. During spermatogenesis, likely involved in spermatocyte centriole cohesion, thus preventing their separation during the second meiotic division. Belongs to the rad21 family. Highly divergent. | 0.811 |
| ZK430.5 | smc-3 | ZK430.5.1 | Y47D3A.26b.1 | Peptidase C50 domain-containing protein. | Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in the repair of double strand breaks during mitosis and meiosis. Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chrom [...] | 0.984 |
| ZK430.5 | wapl-1 | ZK430.5.1 | R08C7.10b.1 | Peptidase C50 domain-containing protein. | Wings apart-like protein homolog 1; Regulator of meiotic chromosome structure and function, playing a role in sister chromatid cohesion, possibly via antagonizing the coh-3/-4 association with axial elements in nuclei during late prophase, cohesin association with chromatin, DNA double strand break repair and polar body positioning following meiotic divisions during oogenesis. Regulates the morphogenesis and temporal assembly of axial elements to control the organization of meiotic chromosomes in pachytene nuclei and is also involved in meiotic chromosomal remodeling in late pachytene [...] | 0.702 |
| coh-3 | ZK430.5 | F08H9.1.1 | ZK430.5.1 | Rad21_Rec8 domain-containing protein. | Peptidase C50 domain-containing protein. | 0.806 |
| coh-3 | him-3 | F08H9.1.1 | ZK381.1a.2 | Rad21_Rec8 domain-containing protein. | HORMA domain-containing protein. | 0.863 |
| coh-3 | htp-1 | F08H9.1.1 | F41H10.10.1 | Rad21_Rec8 domain-containing protein. | HORMA domain-containing protein. | 0.801 |
| coh-3 | htp-3 | F08H9.1.1 | F57C9.5.1 | Rad21_Rec8 domain-containing protein. | HORMA domain-containing protein. | 0.937 |
| coh-3 | lab-1 | F08H9.1.1 | C03D6.6.1 | Rad21_Rec8 domain-containing protein. | Long arms of the bivalent protein 1; Involved in sister chromatid cohesion during mitosis and meiosis. In association with the gsp-2 phosphatase, it both restricts the localization and antagonizes the function of the air-2 kinase during meiosis I and mitosis to promote chromatid cohesion and spindle attachment. This in turn, drives germ cell immortality. Furthermore, may play a role in ensuring the timely assembly of the synaptonemal complex during prophase I of meiosis. | 0.777 |
| coh-3 | rad-51 | F08H9.1.1 | Y43C5A.6a.1 | Rad21_Rec8 domain-containing protein. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.768 |
| coh-3 | rec-8 | F08H9.1.1 | W02A2.6a.1 | Rad21_Rec8 domain-containing protein. | Meiotic recombination protein rec-8; Plays a role in meiotic chromosome cohesion and segregation. Necessary for sister chromatid co- orientation and sister chromatid cohension until meiosis II. May also be required for repair of programmed meiotic double stranded breaks. During spermatogenesis, likely involved in spermatocyte centriole cohesion, thus preventing their separation during the second meiotic division. Belongs to the rad21 family. Highly divergent. | 0.947 |
| coh-3 | sep-1 | F08H9.1.1 | Y47G6A.12.2 | Rad21_Rec8 domain-containing protein. | Separin homolog sep-1; Cysteine protease, which plays a central role in homologous chromosome separation during meiosis I and in sister chromatid separation during embryonic mitosis. Promotes chromosome/sister chromatid segregation by cleaving the scc-1 (mitosis) and rec-8 (meiosis) subunits of the cohesin complex at the onset of anaphase (Probable). May cleave histone H3-like protein cpar-1 during meiosis I metaphase- anaphase transition. Promotes cortical granule exocytosis after oocyte fertilization during the first meiotic anaphase. Essential for embryonic cytokinesis by regulating [...] | 0.843 |
| coh-3 | smc-3 | F08H9.1.1 | Y47D3A.26b.1 | Rad21_Rec8 domain-containing protein. | Structural maintenance of chromosomes protein 3; Involved in chromosome cohesion during cell cycle and in DNA repair. Involved in the repair of double strand breaks during mitosis and meiosis. Required for chromosome segregation during mitosis. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chrom [...] | 0.854 |
| coh-3 | wapl-1 | F08H9.1.1 | R08C7.10b.1 | Rad21_Rec8 domain-containing protein. | Wings apart-like protein homolog 1; Regulator of meiotic chromosome structure and function, playing a role in sister chromatid cohesion, possibly via antagonizing the coh-3/-4 association with axial elements in nuclei during late prophase, cohesin association with chromatin, DNA double strand break repair and polar body positioning following meiotic divisions during oogenesis. Regulates the morphogenesis and temporal assembly of axial elements to control the organization of meiotic chromosomes in pachytene nuclei and is also involved in meiotic chromosomal remodeling in late pachytene [...] | 0.825 |
| him-3 | ZK430.5 | ZK381.1a.2 | ZK430.5.1 | HORMA domain-containing protein. | Peptidase C50 domain-containing protein. | 0.454 |
| him-3 | coh-3 | ZK381.1a.2 | F08H9.1.1 | HORMA domain-containing protein. | Rad21_Rec8 domain-containing protein. | 0.863 |
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